CORE EV
Core Facility · Extracellular Vesicles

The platform for extracellular vesicle science.

Comprehensive isolation, characterisation, and analysis of EVs and nanoparticles — built for reproducibility and publication-ready results.

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Extracellular vesicle research at CORE EV
What we do

Isolation, characterisation, and analysis of EVs at scale.

The CORE EV Facility provides comprehensive services for the isolation, quantification, and characterisation of extracellular vesicles and other nanoparticles — including liposomes, lipid nanoparticles (LNP), and viral particles (lentivirus).

We combine state-of-the-art instrumentation with deep methodological expertise so that every dataset is reproducible, rigorous, and ready for high-impact publication.

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The CORE EV facility

The facility by the numbers.

< 20 nm
Single-molecule resolution
Morphological imaging via Oxford NanoImager dSTORM
3
Orthogonal isolation methods
Differential UC, density gradient UC, and SEC
9+
Core instruments
Covering isolation through biochemical characterisation
Services

Expert EV services, end to end.

From sample receipt to publication-ready data. Every workflow is tailored to your biological question.

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Differential ultracentrifugation, density gradient ultracentrifugation, and size exclusion chromatography — alone or combined — to isolate EVs from any biological matrix.

Equipment

State-of-the-art instrumentation.

Our suite covers every step — from EV isolation through single-particle immunophenotyping.

NTA
Nanosight LM10
Malvern Panalytical
Nanoparticle tracking analysis for size distribution and concentration measurements.
NTA · Zeta Potential
ZetaView Twin
Particle Metrix
Dual-laser NTA with direct zeta potential and fluorescence detection for size, concentration, and surface charge.
Super-resolution
Oxford NanoImager
ONI
Single-molecule dSTORM imaging for nanoscale morphological assessment of EVs.
AF4 · MALS
Eclipse + Dawn Helios-II
Wyatt Technology
Asymmetrical flow field-flow fractionation coupled to multi-angle light scattering, UV and fluorescence detectors.
Ultracentrifugation
Optima XPN-80
Beckman Coulter (×2)
Differential & density gradient UC with SW32.1 and SW55 rotors.
High-speed
Avanti JXN-26
Beckman Coulter
High-speed centrifugation for pre-clearing and large-EV pellet preparation.
Benchtop
Centrifuge 5810 R
Eppendorf (×3)
Refrigerated benchtop centrifugation for routine EV sample preparation workflows.
Automated SEC
Ascent
Everest Biolabs
Automated EV isolation via SEC — up to 8 columns in parallel, 12 fractions per column, programmable fraction collection.
Liquid Handler
Biomek 4000
Beckman Coulter
Robotic workstation for automated density gradient preparation and fraction collection, with HEPA positive-pressure enclosure.
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Ready to start your EV project?

Contact us to discuss your research needs. We will design a workflow tailored to your sample type and scientific question.

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CORE EV is a core facility withinGhent University